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Welcome to SalComFit - the comparative
Salmonella
Typhimurium S. Typhi & S. Paratyphi
Gene Fitness Compendium
Columns of the Heat Maps can be sorted by value - just click on the headers
(
15
30
45
60
75
90
° rotated)
Instructions:
Search by gene, locus or location (multiple entries separated by comma or space, use '*' for wild-card).
*To start:
enter query or select
Example:
cys*
•
Cluster 10
•
Cluster 16
•
Cluster 31
•
Cluster 33
•
motility genes
•
SPI1 genes
•
SPI2
•
SPI1 & 2 effectors
•
SPI3
•
SPI4
•
SPI5
•
SPI6
•
SPI9
•
SPI11
•
SPI12 + oaf O-antigen locus
•
SPI13
•
SPI14
•
SPI16
•
LPS-synthesis
Fitness heat map for 7 IDs in 4/74, D23580, Ty2, Para9150
Colour legend:
4/74
D23580
Ty2
Para9150
query
NonSPI2
InSPI2
InSPI2 Mg
M9 glucose
Bile
Iron limitation
NaCl
Heat
LB
Ceftriaxone
Ciprofloxacin
Azithromycin
Hydrogen peroxide
Nitric oxide
Sodium hypochlorite
Anaerobic
GMM
Zinc overload
N media
Protamine
Gentamycin
Cotrimoxazole
Rifampicin
Polymyxin B
THP-1 Macrophage
NonSPI2
InSPI2
InSPI2 Mg
M9 glucose
Bile
Iron limitation
NaCl
Heat
LB
Ceftriaxone
Ciprofloxacin
Azithromycin
Hydrogen peroxide
Nitric oxide
Sodium hypochlorite
Anaerobic
GMM
Zinc overload
N media
Protamine
Gentamycin
Cotrimoxazole
Rifampicin
Polymyxin B
THP-1 Macrophage
NonSPI2
InSPI2
InSPI2 Mg
M9 glucose
Bile
Iron limitation
NaCl
Heat
LB
Ceftriaxone
Ciprofloxacin
Azithromycin
Hydrogen peroxide
Nitric oxide
Sodium hypochlorite
Anaerobic
GMM
Zinc overload
N media
Protamine
Gentamycin
Cotrimoxazole
Rifampicin
Polymyxin B
THP-1 Macrophage
NonSPI2
InSPI2
InSPI2 Mg
M9 glucose
Bile
Iron limitation
NaCl
Heat
LB
Ceftriaxone
Ciprofloxacin
Azithromycin
Hydrogen peroxide
Nitric oxide
Sodium hypochlorite
Anaerobic
GMM
Zinc overload
N media
Protamine
Gentamycin
Cotrimoxazole
Rifampicin
Polymyxin B
THP-1 Macrophage
Gene Name
Gene Synonym
Multicopy genes
4/74 locus1
4/74 locus2
D23580 locus1
D23580 locus2
Ty2 locus1
Ty2 locus2
Para9150 locus1
Para9150 locus2
LT2 gene
MG1655 gene
Product
arnA
-1.11
-1.04
-1
-1.1
-1.06
-1.08
1.02
-1.07
-1.04
-1.04
-1.31
-1.19
1
-1.27
1.02
-1.04
-1.01
-1.13
-1.01
-1.04
-1.14
-1.25
-1.1
-53.53
1.46
1.02
1.01
1.12
-1.02
-1.1
1.05
-1.05
1
1.12
1.08
-1.22
-1.09
-1.04
-1.01
-1.04
1.05
1.01
-1.1
-1.02
1.07
1.08
-1.07
-1
-72.61
1.52
-1.05
-1.07
-1.3
-1.05
-1.07
-1.02
-1
1
1.05
1.03
-1.03
-1.16
-1.01
-1.11
-1.04
-1.05
-1.07
-1.19
1.01
-1.08
1.11
-1.11
-1.84
-1.87
1.14
-1.04
-1.26
-1.1
-1.05
-1
-1.04
-1.02
1.01
1.1
1.08
1.03
1.08
-1.18
-1.06
-1.26
1.05
1.02
1.02
1.05
-1.05
-1.08
1.03
-1.08
1.02
1.16
arnA
pmrI; yfbG
STM474_RS11800
STM474_2395
STMMW_RS11995
STMMW_23231
T_RS02860
t0564
SPA_RS02830
SPA0564
yfbG
arnA
bifunctional UDP‑4‑amino‑4‑deoxy‑L‑arabinose formyltransferase/UDP‑glucuronic acid oxidase ArnA
arnB
1
-1.07
1.02
-1.04
-1.03
-1.03
-1.07
1.1
1.14
1.13
-1.04
-1.06
-1.13
-1.24
-1.07
1.28
1.08
1.1
1.12
1.05
-1.05
-1.07
-1.06
-36.4
2.18
-1.11
-1.09
-1.01
-1.11
-1.1
1
-1.06
-1.07
-1.06
1.04
-1.19
-1.21
1.04
-1.05
-1.05
1.16
1.04
-1.08
-1.01
1.03
-1.09
1.09
-1.1
-46.85
2.05
1.04
-1.05
-1.3
-1.05
1.06
1.05
1.08
1.12
1.04
-1.03
-1.08
1.01
1.13
-1.01
-1.03
1.04
1.09
-1.08
1.03
1.07
1.07
-1.06
-1.61
-1.93
1.34
-1.01
-1.35
-1.19
1.02
1.03
1.01
-1
1.02
1.04
1.02
-1.03
-1.01
-1.21
1.08
-1.15
1.02
1.07
1
1.05
1.01
1.09
1.09
-1.07
-1.1
1.33
arnB
pmrH; yfbE
STM474_RS11790
STM474_2393
STMMW_RS11985
STMMW_23211
T_RS02870
t0566
SPA_RS02840
SPA0566
yfbE
arnB
UDP‑4‑amino‑4‑deoxy‑L‑arabinose aminotransferase
arnC
1.05
1.01
1.02
-1.01
-1.07
-1
1
-1.01
1.07
1.09
-1.02
-1.15
-1.01
-1.23
-1.09
1.02
1.03
-1.08
1.07
1.1
-1
-1.04
1.01
-25.37
1.67
-1.01
-1.07
1.04
-1.05
-1.08
-1.03
-1.03
-1.01
1.02
1
-1.12
-1.25
-1.04
-1
-1.08
1.01
-1
-1.17
1
1.01
1.06
-1.01
-1.09
-75.99
1.12
1
-1.04
-1.29
-1.03
-1.03
1.02
1.02
1
-1.05
1
-1.04
-1.13
-1.07
-1.09
-1.1
-1.02
-1
-1.15
1.06
1.03
1.11
1.03
-1.5
-1.89
1.1
-1.03
-1.36
-1.21
-1
1.01
1.07
1.05
1.02
1.05
1.04
1.02
1.03
-1.2
-1.01
-1.17
1.04
-1
1.02
1.01
-1.01
1.02
1.08
1.02
-1
1.05
arnC
pmrF
STM474_RS11795
STM474_2394
STMMW_RS11990
STMMW_23221
T_RS02865
t0565
SPA_RS02835
SPA0565
pmrF
arnC
undecaprenyl‑phosphate 4‑deoxy‑4‑formamido‑L‑arabinose transferase
arnD
1.23
-1.14
-1.12
1.17
1
1.2
1.03
1.12
1.29
1.66
1.5
2
-17.41
-16.16
-1.05
1.12
1.12
-1.19
1.17
-1.18
-1.31
1.67
1.44
-41.76
2.1
1.13
1.08
1.07
1.16
-1.04
1.18
-1.03
1
1.24
1.7
2.55
2.14
1.24
-1.15
1.16
1.2
1.06
-1.14
1.31
-2.32
1.05
1.14
1.74
-73.03
-2.13
1.18
1.04
-1.36
1.19
-1.09
1.04
1.09
1.03
1.04
1.18
1.27
2.08
-1.07
1.05
-1.02
-1.01
1.14
-2.69
1.17
-4.46
-1.02
1.38
4.08
-2.7
-4.44
1.03
-1.49
-1.41
1.18
-1
-1
-1.11
-1.06
-1
-1
1.15
1.03
-2.27
-1.64
-2.04
1.07
1.06
-1.05
1.04
-1.16
-1.25
1.06
1.05
1
-1.13
arnD
pmrJ; arnD
STM474_RS11805
STM474_2396
STMMW_RS12000
STMMW_23241
T_RS02855
t0563
SPA_RS02825
SPA0563
pbgP4
arnD
4‑deoxy‑4‑formamido‑L‑arabinose‑ phosphoundecaprenol deformylase
arnE
1.01
-5.65
-12.77
1.07
1.06
1.24
1.01
1.3
-1.12
-23.61
1.26
2.49
-23.55
-16.19
-6.27
-1.31
1.18
-8.26
1.13
-1.41
1.14
-1.68
1.58
-16.72
-2.01
1.13
-3.97
-8.48
1.1
1.24
1.06
-1.1
-1.21
1.04
-6.47
2.68
1.87
-2.39
-5.69
-1.1
1.22
-1.26
-6.43
1.39
-1.27
-1.07
1.2
1.43
-29.14
-13
1.22
-4.41
-8.8
1.24
1.08
1.12
1.42
1.23
1.1
1.09
1.34
3.25
-2.28
-4.61
-1.49
1.15
1.21
-5.75
1.08
-2.34
1.04
-2.05
4.76
-1.57
-1.04
1
-1.47
-3.15
1.11
-1.02
1.07
1.15
1.1
1.1
1.05
1.07
1.06
-1.39
-1.3
-1.32
1.09
1.12
1.02
1.22
1.03
1.25
1.1
1.06
1.12
1.08
arnE
STM474_RS11815
STM474_2398
STMMW_RS12010
STMMW_23261
T_RS02845
t0561
SPA_RS02815
SPA0561
STM2302
arnE
4‑amino‑4‑deoxy‑L‑arabinose‑phosphoundecaprenol flippase subunit ArnE
arnF
1.14
-12.06
-6.59
1.07
1.15
1.18
1.08
-1.03
1.09
-6.08
1.76
1.95
-30.04
-51.22
-4.61
1.02
-1.06
-6.98
1.15
-1.03
-1.24
-1.39
1.29
-27.22
-2.28
1.03
-4.54
-6.45
-1.18
1.16
1.54
1.4
1.16
1.2
-7.06
1.84
1.78
-3.01
-8.46
-1.85
-1.1
1.11
-6.16
1.06
-1.13
-1.52
1.2
1.05
-55.86
2.25
1.3
-3.15
-6.5
1.19
1
1.2
1.37
1.12
1.17
-1.16
1.32
2.76
-2.06
-3.03
-1.34
1
1.13
-5.55
1.07
-3.2
1.33
-1.44
6.01
-1.25
-2.21
-1.15
-1.44
-2.5
1.06
1.04
-1.01
-1.04
1.03
1
1
1.23
1.2
-1.28
-1.31
-1.3
-1
1
-1.11
-1.15
-1.11
1.25
1.18
1.08
1.16
1
arnF
pmrM
STM474_RS11820
STM474_2399
STMMW_RS12015
STMMW_23271
T_RS02840
t0560
SPA_RS02810
SPA0560
STM2303
arnF
4‑amino‑4‑deoxy‑L‑arabinose‑phosphoundecaprenol flippase subunit ArnF
arnT
-1.04
-1.01
1.1
-1.02
-1.06
-1.02
-1
1.05
1.03
-1.38
-1.06
1.04
-1.26
-2.11
-1.18
1.07
-1.04
1.04
1.04
1.05
1.03
-1.08
1.06
-28.83
1.51
1
-1.06
1.13
-1.02
-1.05
-1.02
-1.05
-1.06
1.01
1.12
1.11
1.09
1.02
-1.07
-1.08
1.05
1.05
1.06
1.05
1.1
1.01
1.03
1.08
-62.93
-1.12
1.07
-1.09
-1.46
1.03
-1.08
1
1.03
-1.07
1.02
-1
-1
1.04
-1.12
-1.05
-1.09
-1.01
1.07
-1.4
1.08
-1.17
1.04
1.01
-1.1
-1.94
-1.56
-1.06
-1.35
-1.27
1.03
-1.01
1
-1.02
-1
1.05
1.01
1.11
1.06
-1.48
-1.23
-1.39
1
1.04
1
1.06
-1.02
1.06
1.08
1.06
-1.05
-1.12
arnT
pqaB; pmrK
STM474_RS11810
STM474_2397
STMMW_RS12005
STMMW_23251
T_RS02850
t0562
SPA_RS02820
SPA0562
pqaB
arnT
lipid IV(A) 4‑amino‑4‑deoxy‑L‑arabinosyltransferase
≤ -4
-1 | 1
≥ 4
Reduced
Fitness
Increased
Fitness
(values represent fold-changes)
download data:
Results provided by the
Monack Lab
, automatically generated on Tue Sep 10 12:16:58 2024
We are very grateful to Joe Grissom and Tyrrell Conway for sharing the code that drives this compendium database, and was originally designed for use at
GenExpDB
.