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Welcome to SalComFit - the comparative
Salmonella Typhimurium S. Typhi & S. Paratyphi
Gene Fitness Compendium
Columns of the Heat Maps can be sorted by value - just click on the headers
(° rotated)
Instructions:  Search by gene, locus or location (multiple entries separated by comma or space, use '*' for wild-card).
*To start:  enter query or select Example: cys*Cluster 10Cluster 16Cluster 31Cluster 33motility genesSPI1 genesSPI2SPI1 & 2 effectorsSPI3SPI4SPI5SPI6SPI9SPI11SPI12 + oaf O-antigen locusSPI13SPI14SPI16LPS-synthesis

Fitness heat map for 7 IDs in 4/74, D23580, Ty2, Para9150

Colour legend:4/74 D23580 Ty2 Para9150

query
NonSPI2
InSPI2
InSPI2 Mg
M9 glucose
Bile
Iron limitation
NaCl
Heat
LB
Ceftriaxone
Ciprofloxacin
Azithromycin
Hydrogen peroxide
Nitric oxide
Sodium hypochlorite
Anaerobic
GMM
Zinc overload
N media
Protamine
Gentamycin
Cotrimoxazole
Rifampicin
Polymyxin B
THP-1 Macrophage
NonSPI2
InSPI2
InSPI2 Mg
M9 glucose
Bile
Iron limitation
NaCl
Heat
LB
Ceftriaxone
Ciprofloxacin
Azithromycin
Hydrogen peroxide
Nitric oxide
Sodium hypochlorite
Anaerobic
GMM
Zinc overload
N media
Protamine
Gentamycin
Cotrimoxazole
Rifampicin
Polymyxin B
THP-1 Macrophage
NonSPI2
InSPI2
InSPI2 Mg
M9 glucose
Bile
Iron limitation
NaCl
Heat
LB
Ceftriaxone
Ciprofloxacin
Azithromycin
Hydrogen peroxide
Nitric oxide
Sodium hypochlorite
Anaerobic
GMM
Zinc overload
N media
Protamine
Gentamycin
Cotrimoxazole
Rifampicin
Polymyxin B
THP-1 Macrophage
NonSPI2
InSPI2
InSPI2 Mg
M9 glucose
Bile
Iron limitation
NaCl
Heat
LB
Ceftriaxone
Ciprofloxacin
Azithromycin
Hydrogen peroxide
Nitric oxide
Sodium hypochlorite
Anaerobic
GMM
Zinc overload
N media
Protamine
Gentamycin
Cotrimoxazole
Rifampicin
Polymyxin B
THP-1 Macrophage
    Gene Name Gene Synonym Multicopy genes 4/74 locus1 4/74 locus2 D23580 locus1 D23580 locus2 Ty2 locus1 Ty2 locus2 Para9150 locus1 Para9150 locus2 LT2 gene MG1655 gene Product
arnA  -1.11 -1.04 -1 -1.1 -1.06 -1.08 1.02 -1.07 -1.04 -1.04 -1.31 -1.19 1 -1.27 1.02 -1.04 -1.01 -1.13 -1.01 -1.04 -1.14 -1.25 -1.1 -53.53   1.46   1.02 1.01 1.12 -1.02 -1.1 1.05 -1.05 1 1.12 1.08 -1.22 -1.09 -1.04 -1.01 -1.04 1.05 1.01 -1.1 -1.02 1.07 1.08 -1.07 -1 -72.61   1.52   -1.05 -1.07 -1.3 -1.05 -1.07 -1.02 -1 1 1.05 1.03 -1.03 -1.16 -1.01 -1.11 -1.04 -1.05 -1.07 -1.19 1.01 -1.08 1.11 -1.11 -1.84 -1.87   1.14   -1.04 -1.26 -1.1 -1.05 -1 -1.04 -1.02 1.01 1.1 1.08 1.03 1.08 -1.18 -1.06 -1.26 1.05 1.02 1.02 1.05 -1.05 -1.08 1.03 -1.08 1.02   1.16   arnA pmrI; yfbG STM474_RS11800 STM474_2395 STMMW_RS11995 STMMW_23231 T_RS02860 t0564 SPA_RS02830 SPA0564 yfbG arnA bifunctional UDP‑4‑amino‑4‑deoxy‑L‑arabinose formyltransferase/UDP‑glucuronic acid oxidase ArnA
arnB  1 -1.07 1.02 -1.04 -1.03 -1.03 -1.07 1.1 1.14 1.13 -1.04 -1.06 -1.13 -1.24 -1.07 1.28 1.08 1.1 1.12 1.05 -1.05 -1.07 -1.06 -36.4   2.18   -1.11 -1.09 -1.01 -1.11 -1.1 1 -1.06 -1.07 -1.06 1.04 -1.19 -1.21 1.04 -1.05 -1.05 1.16 1.04 -1.08 -1.01 1.03 -1.09 1.09 -1.1 -46.85   2.05   1.04 -1.05 -1.3 -1.05 1.06 1.05 1.08 1.12 1.04 -1.03 -1.08 1.01 1.13 -1.01 -1.03 1.04 1.09 -1.08 1.03 1.07 1.07 -1.06 -1.61 -1.93   1.34   -1.01 -1.35 -1.19 1.02 1.03 1.01 -1 1.02 1.04 1.02 -1.03 -1.01 -1.21 1.08 -1.15 1.02 1.07 1 1.05 1.01 1.09 1.09 -1.07 -1.1   1.33   arnB pmrH; yfbE STM474_RS11790 STM474_2393 STMMW_RS11985 STMMW_23211 T_RS02870 t0566 SPA_RS02840 SPA0566 yfbE arnB UDP‑4‑amino‑4‑deoxy‑L‑arabinose aminotransferase
arnC  1.05 1.01 1.02 -1.01 -1.07 -1 1 -1.01 1.07 1.09 -1.02 -1.15 -1.01 -1.23 -1.09 1.02 1.03 -1.08 1.07 1.1 -1 -1.04 1.01 -25.37   1.67   -1.01 -1.07 1.04 -1.05 -1.08 -1.03 -1.03 -1.01 1.02 1 -1.12 -1.25 -1.04 -1 -1.08 1.01 -1 -1.17 1 1.01 1.06 -1.01 -1.09 -75.99   1.12   1 -1.04 -1.29 -1.03 -1.03 1.02 1.02 1 -1.05 1 -1.04 -1.13 -1.07 -1.09 -1.1 -1.02 -1 -1.15 1.06 1.03 1.11 1.03 -1.5 -1.89   1.1   -1.03 -1.36 -1.21 -1 1.01 1.07 1.05 1.02 1.05 1.04 1.02 1.03 -1.2 -1.01 -1.17 1.04 -1 1.02 1.01 -1.01 1.02 1.08 1.02 -1   1.05   arnC pmrF STM474_RS11795 STM474_2394 STMMW_RS11990 STMMW_23221 T_RS02865 t0565 SPA_RS02835 SPA0565 pmrF arnC undecaprenyl‑phosphate 4‑deoxy‑4‑formamido‑L‑arabinose transferase
arnD  1.23 -1.14 -1.12 1.17 1 1.2 1.03 1.12 1.29 1.66 1.5 2 -17.41 -16.16 -1.05 1.12 1.12 -1.19 1.17 -1.18 -1.31 1.67 1.44 -41.76   2.1   1.13 1.08 1.07 1.16 -1.04 1.18 -1.03 1 1.24 1.7 2.55 2.14 1.24 -1.15 1.16 1.2 1.06 -1.14 1.31 -2.32 1.05 1.14 1.74 -73.03   -2.13   1.18 1.04 -1.36 1.19 -1.09 1.04 1.09 1.03 1.04 1.18 1.27 2.08 -1.07 1.05 -1.02 -1.01 1.14 -2.69 1.17 -4.46 -1.02 1.38 4.08 -2.7   -4.44   1.03 -1.49 -1.41 1.18 -1 -1 -1.11 -1.06 -1 -1 1.15 1.03 -2.27 -1.64 -2.04 1.07 1.06 -1.05 1.04 -1.16 -1.25 1.06 1.05 1   -1.13   arnD pmrJ; arnD STM474_RS11805 STM474_2396 STMMW_RS12000 STMMW_23241 T_RS02855 t0563 SPA_RS02825 SPA0563 pbgP4 arnD 4‑deoxy‑4‑formamido‑L‑arabinose‑ phosphoundecaprenol deformylase
arnE  1.01 -5.65 -12.77 1.07 1.06 1.24 1.01 1.3 -1.12 -23.61 1.26 2.49 -23.55 -16.19 -6.27 -1.31 1.18 -8.26 1.13 -1.41 1.14 -1.68 1.58 -16.72   -2.01   1.13 -3.97 -8.48 1.1 1.24 1.06 -1.1 -1.21 1.04 -6.47 2.68 1.87 -2.39 -5.69 -1.1 1.22 -1.26 -6.43 1.39 -1.27 -1.07 1.2 1.43 -29.14   -13   1.22 -4.41 -8.8 1.24 1.08 1.12 1.42 1.23 1.1 1.09 1.34 3.25 -2.28 -4.61 -1.49 1.15 1.21 -5.75 1.08 -2.34 1.04 -2.05 4.76 -1.57   -1.04   1 -1.47 -3.15 1.11 -1.02 1.07 1.15 1.1 1.1 1.05 1.07 1.06 -1.39 -1.3 -1.32 1.09 1.12 1.02 1.22 1.03 1.25 1.1 1.06 1.12   1.08   arnE STM474_RS11815 STM474_2398 STMMW_RS12010 STMMW_23261 T_RS02845 t0561 SPA_RS02815 SPA0561 STM2302 arnE 4‑amino‑4‑deoxy‑L‑arabinose‑phosphoundecaprenol flippase subunit ArnE
arnF  1.14 -12.06 -6.59 1.07 1.15 1.18 1.08 -1.03 1.09 -6.08 1.76 1.95 -30.04 -51.22 -4.61 1.02 -1.06 -6.98 1.15 -1.03 -1.24 -1.39 1.29 -27.22   -2.28   1.03 -4.54 -6.45 -1.18 1.16 1.54 1.4 1.16 1.2 -7.06 1.84 1.78 -3.01 -8.46 -1.85 -1.1 1.11 -6.16 1.06 -1.13 -1.52 1.2 1.05 -55.86   2.25   1.3 -3.15 -6.5 1.19 1 1.2 1.37 1.12 1.17 -1.16 1.32 2.76 -2.06 -3.03 -1.34 1 1.13 -5.55 1.07 -3.2 1.33 -1.44 6.01 -1.25   -2.21   -1.15 -1.44 -2.5 1.06 1.04 -1.01 -1.04 1.03 1 1 1.23 1.2 -1.28 -1.31 -1.3 -1 1 -1.11 -1.15 -1.11 1.25 1.18 1.08 1.16   1   arnF pmrM STM474_RS11820 STM474_2399 STMMW_RS12015 STMMW_23271 T_RS02840 t0560 SPA_RS02810 SPA0560 STM2303 arnF 4‑amino‑4‑deoxy‑L‑arabinose‑phosphoundecaprenol flippase subunit ArnF
arnT  -1.04 -1.01 1.1 -1.02 -1.06 -1.02 -1 1.05 1.03 -1.38 -1.06 1.04 -1.26 -2.11 -1.18 1.07 -1.04 1.04 1.04 1.05 1.03 -1.08 1.06 -28.83   1.51   1 -1.06 1.13 -1.02 -1.05 -1.02 -1.05 -1.06 1.01 1.12 1.11 1.09 1.02 -1.07 -1.08 1.05 1.05 1.06 1.05 1.1 1.01 1.03 1.08 -62.93   -1.12   1.07 -1.09 -1.46 1.03 -1.08 1 1.03 -1.07 1.02 -1 -1 1.04 -1.12 -1.05 -1.09 -1.01 1.07 -1.4 1.08 -1.17 1.04 1.01 -1.1 -1.94   -1.56   -1.06 -1.35 -1.27 1.03 -1.01 1 -1.02 -1 1.05 1.01 1.11 1.06 -1.48 -1.23 -1.39 1 1.04 1 1.06 -1.02 1.06 1.08 1.06 -1.05   -1.12   arnT pqaB; pmrK STM474_RS11810 STM474_2397 STMMW_RS12005 STMMW_23251 T_RS02850 t0562 SPA_RS02820 SPA0562 pqaB arnT lipid IV(A) 4‑amino‑4‑deoxy‑L‑arabinosyltransferase

                                                                                   
 ≤ -4 -1 | 1  ≥ 4
Reduced
Fitness
Increased
Fitness
(values represent fold-changes)
download data: download data as tab-delimited text file



Results provided by the Monack Lab, automatically generated on Tue Sep 10 12:16:58 2024
We are very grateful to Joe Grissom and Tyrrell Conway for sharing the code that drives this compendium database, and was originally designed for use at GenExpDB.